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Indulgent Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce

Published: Aug 15, 2025 by Dia Martinez · This post may contain affiliate links · Leave a Comment

The aroma of tender beef simmering away in my Instant Pot brings me back to cozy family gatherings filled with laughter and warmth. Today, I'm thrilled to share my take on Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce—a comforting dish that's perfect for any weeknight. Not only is this recipe a breeze to whip up, but it’s also a guaranteed crowd-pleaser that will have everyone reaching for seconds. Picture juicy beef enveloped in a rich, creamy cheese sauce with just the right amount of spice, all nestled between soft, toasted buns. Whether you're tending to a busy schedule or simply seeking a fulfilling meal for your loved ones, this savory delight has you covered. Ready to savor a taste of home-cooked happiness? Let’s dive into the details!

Why are these sandwiches so irresistible?

Simplicity: This recipe comes together in just a few easy steps, making it perfect for busy weeknights.

Delicious Comfort Food: The combination of tender beef and spicy cheese sauce offers a warm, inviting taste that feels like a hug in sandwich form.

Crowd-Pleaser: Ideal for gatherings, these sandwiches ensure your guests will return for seconds, if not thirds!

Flavorful Twist: The spicy cheese sauce adds a delightful kick, elevating classic flavors and exciting your palate.

Versatile Options: Want to mix it up? Substitute the meat or adjust the spice level for tailored taste experiences. Whether you’re cooking for a family dinner or a cozy night in, pair these with crispy oven-baked fries for a full meal that satisfies!

Instant Pot Beef and Cheddar Sandwiches Ingredients

• All the essentials for your delicious meal!

For the Sandwich Filling
• Thinly Sliced Beef – Provides the main protein and savory backbone; look for quality cuts like top round roast.
• Beef Broth – Enhances flavor and moisture during cooking; can substitute with vegetable broth for a lighter taste.
• Garlic Powder – Adds depth and aroma; fresh garlic can also be used if preferred.
• Salt & Pepper – Essential for seasoning to elevate the dish's overall flavor; adjust to taste.

For the Cheese Sauce
• Unsalted Butter – Creates a roux for the cheese sauce, achieving a rich texture; can substitute with olive oil for dairy-free.
• All-Purpose Flour – Thickens the cheese sauce, giving it body; gluten-free flour can serve as a substitute.
• Milk – Forms the base of the cheese sauce; can replace with dairy-free alternatives like oat or almond milk.
• Hot Sauce – Provides a spicy kick; adjust quantity for heat preference.
• Sharp Cheddar Cheese – Primary flavor for the cheese sauce to ensure a cheesy melt; use freshly grated cheese for best results.

For the Assembly
• Onion Hamburger Buns – Serves as the sandwich base, and toasting adds texture and prevents sogginess.

There you have it, everything you need! Get ready to indulge in these Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce!

Step‑by‑Step Instructions for Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce

Step 1: Prepare Ingredients
Begin by gathering all your ingredients for the Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce. Measure out the thinly sliced beef, beef broth, garlic powder, salt, and pepper for easy access. For the cheese sauce, have the unsalted butter, flour, milk, hot sauce, and sharp cheddar cheese ready to go. This sets the stage for a smooth cooking process.

Step 2: Cook Beef
Place the thinly sliced beef into the Instant Pot along with the beef broth, garlic powder, salt, and pepper. Secure the lid tightly, ensuring the pressure valve is closed. Set the Instant Pot to cook on High Pressure for 10 minutes. Once the cooking time is complete, let the pressure release naturally for 10 minutes before carefully switching to quick release to remove any remaining pressure.

Step 3: Make Cheese Sauce
While the beef is resting, prepare the spicy cheese sauce. In a medium saucepan over medium heat, melt the unsalted butter. Whisk in the all-purpose flour to form a roux, cooking for about 1–2 minutes until it’s lightly golden. Slowly add the milk while whisking consistently to avoid lumps, cooking until the mixture thickens, about 3–5 minutes. Stir in hot sauce and shredded sharp cheddar cheese until melted and smooth.

Step 4: Assemble Sandwiches
Toast the onion hamburger buns in the oven or on a skillet until golden brown. This step is essential for preventing sogginess from the cheese sauce. Once toasted, pile the cooked beef generously onto the bottom half of the buns. Drizzle the creamy, spicy cheese sauce over the beef, allowing it to cascade delightfully onto the bun.

Step 5: Serve
Finally, place the top half of the buns over the cheese-covered beef and serve your Instant Pot Beef and Cheddar Sandwiches warm. For an extra touch, consider garnishing with sliced pickles or chopped green onions. Pair with crispy oven-baked fries for a full meal that’s sure to delight!

Expert Tips for Instant Pot Beef and Cheddar Sandwiches

  • Fresh Cheese: Use freshly grated sharp cheddar cheese for optimal melting and creaminess in your cheese sauce. Pre-packaged cheese can often have anti-caking agents that can affect texture.

  • Prevent Sogginess: Toast the hamburger buns before assembling to maintain their integrity against the delicious, spicy cheese sauce. This simple step helps keep your sandwiches delightful to the last bite.

  • Manage Pressure Wisely: Be cautious when releasing pressure from the Instant Pot. Allow some natural release time before switching to quick release; this prevents splattering and ensures the beef remains tender.

  • Storage Tips: Store any leftover beef and cheese sauce separately in airtight containers for freshness. This prevents sogginess in the buns and allows you to reheat just what you need of the Instant Pot Beef and Cheddar Sandwiches.

  • Customize Spice Levels: Adjust the amount of hot sauce in your cheese sauce according to your heat preference. For a milder version, start with less and add more to taste.

What to Serve with Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce?

Complete your meal with these delicious pairings that enhance the flavors of your beefy creation and satisfy your cravings.

  • Crispy Oven-Baked Fries: The crunch of these golden fries adds a satisfying texture contrast while soaking up the spicy cheese sauce drippings. Serve with a sprinkle of sea salt for that classic touch.

  • Simple Green Salad: A refreshing salad adorned with mixed greens, cherry tomatoes, and a light vinaigrette complements the hearty sandwich while balancing the richness of the beef and cheese.

  • Coleslaw: The crunchy and tangy slaw cuts through the richness, adding a delightful crunch and brightness that elevate every bite. It’s a classic pairing with sandwiches that your family will love!

  • Pickles or Pickled Veggies: These briny bites can brighten up your meal, providing a zesty contrast to the savory beef. They are fantastic for cleansing the palate.

  • Creamy Macaroni and Cheese: For the ultimate comfort food experience, why not double down on cheese? The additional creaminess spares no indulgence for cheese lovers and rounds out the meal delightfully.

  • Iced Tea or Lemonade: A refreshing drink like iced tea, sweetened or unsweetened, or a zesty lemonade can be the perfect thirst quencher while harmonizing with the spicy elements of the sandwich.

  • Chocolate Chip Cookies: For dessert, these warm, gooey cookies offer a sweet finish to your meal, blending nostalgia and happiness in every bite. The perfect way to end a cozy feast!

Make Ahead Options

These Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce are a fantastic option for meal prep! You can cook the beef in advance, refrigerating it in an airtight container for up to 3 days. The cheese sauce can also be made ahead, but for the best texture, prepare it fresh just before serving. To reheat, gently warm the beef in the microwave or on the stovetop, and for the cheese sauce, consider adding a splash of milk to restore its creamy consistency while heating. This way, you’ll save time on busy weeknights while still enjoying all the delicious flavors, just as comforting and satisfying as when they were freshly made!

Instant Pot Beef and Cheddar Sandwiches Variations

Feel free to explore these delightful modifications, and let your creativity shine in the kitchen!

  • Dairy-Free: Substitute unsalted butter with plant-based butter and use dairy-free milk and cheese alternatives for a creamy indulgence.

  • Spicy Kick: Increase the hot sauce or add diced jalapeños to the beef for an extra spicy twist that will tantalize your taste buds.

  • Flavorful Beef Swap: Replace the thinly sliced beef with chuck roast or brisket for a heartier flavor that brings a new dimension to the sandwich.

  • Vegetarian Option: Switch out the beef for sautéed mushrooms or jackfruit, adding a bit of soy sauce for extra umami goodness.

  • Extra Crunch: Add crispy fried onions or coleslaw to your sandwiches for a delightful crunch that complements the creamy cheese sauce beautifully.

  • Smoky Twist: Introduce a bit of smoked paprika into the cheese sauce for a warm, smoky flavor that enhances the overall profile of the dish.

  • Herbed Up: Incorporate fresh herbs like thyme or rosemary into the cheesy sauce for a fragrant addition that brightens the flavors.

  • Mini Sandwiches: Make sliders with smaller buns for bite-sized delights, perfect for gatherings or parties. Serve them with your favorite dipping sauces like ranch or ketchup!

Feel encouraged to try different combinations, and don’t hesitate to make these sandwiches your own with personalized touches! Want to make a meal even heartier? Pair these with tasty crispy oven-baked fries for a complete comfort food experience!

How to Store and Freeze Instant Pot Beef and Cheddar Sandwiches

Fridge: Store leftover beef and cheese sauce in separate airtight containers for up to 3 days to maintain freshness and texture.

Freezer: You can freeze the cooked beef for up to 2 months. Allow it to cool before transferring to a freezer-safe container.

Reheating: When ready to enjoy, thaw the beef overnight in the fridge, then reheat gently on the stove or in the microwave until warmed through.

Assemble Fresh: For best results, reassemble the Instant Pot Beef and Cheddar Sandwiches just before serving to enjoy that warm, cheesy goodness.

Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce Recipe FAQs

What type of beef should I use for these sandwiches?
Absolutely! For the best results, I recommend using thinly sliced cuts like top round roast. They provide a tender and flavorful backbone for the sandwiches. You can also experiment with chuck roast or brisket for different flavor profiles—each will lend a unique taste!

How should I store leftovers?
Store leftover beef and cheese sauce in separate airtight containers in the fridge for up to 3 days. This helps maintain the quality of each component. If you feel adventurous, you can freeze the beef for up to 2 months; just ensure it cools completely before placing it in a freezer-safe container.

Can I freeze the cheese sauce?
I recommend making the cheese sauce fresh, as it tends to lose its creamy texture when frozen. However, if you have leftovers, store them in an airtight container in the fridge and enjoy within 3 days. If you must freeze it, keep in mind it may separate upon thawing, so you might need to reheat gently and stir until smooth.

What can I do if my cheese sauce isn’t thickening?
Very! No worries if your cheese sauce isn't thickening as you'd like. If it seems too thin, allow it to simmer a bit longer while whisking continuously. Alternatively, you can create a slurry by mixing a little more flour with cold milk, then adding it gradually to the sauce while stirring. Cook until it reaches your desired thickness! Remember, patience is key as it will thicken more as it cools.

Are there any dietary considerations for this recipe?
Definitely! For those with dietary restrictions, you can easily modify this recipe. Use plant-based butter, milk, and cheese alternatives to make it dairy-free. If gluten is a concern, substitute all-purpose flour with a gluten-free blend. Also, always check labels on ingredients like hot sauce for potential allergens if you're cooking for others.

How can I adjust the spice level in the cheese sauce?
The more the merrier! Start with a smaller amount of hot sauce and gradually add more to taste, allowing you to customize the heat level to your liking. If you’re unsure, taste as you go—there’s no rush, and it’s better to add than to overpower your cheese sauce!

Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce

Indulgent Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce

Savor the flavors of Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce—a comforting dish perfect for any weeknight.
Print Recipe Pin Recipe
Prep Time 15 minutes mins
Cook Time 20 minutes mins
Natural Pressure Release 10 minutes mins
Total Time 45 minutes mins
Servings: 4 sandwiches
Course: dinner
Cuisine: American
Calories: 550
Ingredients Equipment Method Nutrition Notes

Ingredients
  

For the Sandwich Filling
  • 1 pound thinly sliced beef look for quality cuts like top round roast
  • 1 cup beef broth can substitute with vegetable broth for a lighter taste
  • 1 teaspoon garlic powder fresh garlic can also be used if preferred
  • to taste salt essential for seasoning to elevate the dish's flavor
  • to taste pepper essential for seasoning to elevate the dish's flavor
For the Cheese Sauce
  • 4 tablespoons unsalted butter can substitute with olive oil for dairy-free
  • 1 quarter cup all-purpose flour gluten-free flour can serve as a substitute
  • 1 cup milk can replace with dairy-free alternatives like oat or almond milk
  • to taste hot sauce provides a spicy kick; adjust quantity for heat preference
  • 2 cups sharp cheddar cheese use freshly grated cheese for best results
For the Assembly
  • 4 onion hamburger buns toasting adds texture and prevents sogginess

Equipment

  • Instant Pot
  • medium saucepan

Method
 

Preparation
  1. Gather all your ingredients for the Instant Pot Beef and Cheddar Sandwiches with Spicy Cheese Sauce.
  2. Measure out the thinly sliced beef, beef broth, garlic powder, salt, and pepper.
  3. Have the unsalted butter, flour, milk, hot sauce, and sharp cheddar cheese ready for the cheese sauce.
Cooking
  1. Place the thinly sliced beef into the Instant Pot along with the beef broth, garlic powder, salt, and pepper.
  2. Secure the lid tightly and set to cook on High Pressure for 10 minutes.
  3. Let the pressure release naturally for 10 minutes before switching to quick release.
Making Cheese Sauce
  1. Melt the unsalted butter in a medium saucepan over medium heat.
  2. Whisk in the flour to form a roux and cook for 1-2 minutes until lightly golden.
  3. Slowly add the milk while whisking consistently to avoid lumps; cook until thickened, about 3-5 minutes.
  4. Stir in hot sauce and shredded sharp cheddar cheese until melted and smooth.
Assembling
  1. Toast the onion hamburger buns until golden brown.
  2. Pile the cooked beef generously onto the bottom half of the buns.
  3. Drizzle the creamy, spicy cheese sauce over the beef.
Serving
  1. Place the top half of the buns over the cheese-covered beef and serve warm.
  2. Consider garnishing with sliced pickles or chopped green onions.

Nutrition

Serving: 1sandwichCalories: 550kcalCarbohydrates: 35gProtein: 30gFat: 25gSaturated Fat: 15gPolyunsaturated Fat: 1gMonounsaturated Fat: 5gCholesterol: 70mgSodium: 800mgPotassium: 500mgFiber: 2gSugar: 3gVitamin A: 500IUCalcium: 200mgIron: 2mg

Notes

Store leftover beef and cheese sauce separately in airtight containers for freshness. Reassemble just before serving for the best results.

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Let us know how it was!

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Welcome!

I'm a passionate home cook and recipe developer who has been creating and testing family-friendly recipes for over 8 years. Every recipe on DiaRecipes is tested multiple times in my own kitchen before sharing it with you

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